Experimental Biology and Medicine

Experimental Biology and MedicineJournal of the Society for
Experimental Biology and Medicine

All manuscripts should be submitted to:

http://ebm.allentrack.net

Please read the following instructions prior to submitting your manuscript:

Instructions for Authors

Experimental Biology and Medicine is particularly appropriate for publication of papers that are multidisciplinary in nature, are of potential interest to a wide audience, and represent experimental medicine in the broadest sense of the term. However, manuscripts reporting novel findings on any topic in the realm of experimental biology and medicine are most welcome. We particularly encourage submission of manuscripts that describe results of studies that require an interdisciplinary approach to biomedical issues. Categories currently listed in EBM are: Anatomy/Pathology; Biochemistry and Molecular Biology; Cell and Developmental Biology; Endocrinoogy and Nutrition; Immunology/Microbiology/Virology; Neuroscience; Pharmacology and Toxicology; Physiology; Bioimaging; Biomedical Engineering; Bionanoscience; Genomics, Proteomics, and Bioinformatics; Stem Cell Biology; Systems Biology and Translational Research. Authors should indicate their preference of category, although the final decision of reviewing Associate Editor and section Editorial Board rests with the Editor-in-Chief.

Assistance with English

If English is not your native language, you may find it helpful to obtain assistance in writing your papers before submitting them to EBM. This may not only save time in the review process but also increase the accuracy of your submission. You can find help in scientific writing at several companies that include:

www.biosciencewriters.com
www.bostonbioedit.com
www.prof-editing.com

Please note that neither EBM nor SEBM has used these services and are unable to comment on the quality of their work.

Research Articles

Manuscripts are accepted for review with the understanding that the same work has not been and, if accepted by EBM, will not be published elsewhere nor is presently submitted elsewhere; and that its submission for publication has been approved by all of the authors (as confirmed by the covering letter). Unnecessary subdivision of a study into several manuscripts is not acceptable. If any material published previously is included, for clarity or other reasons, this should be indicated with appropriate citation in the manuscript.

One copy of any material that might be regarded as "duplicate publication," such as preliminary reports (including reviews, symposia and proceedings) or other publications (submitted, in press or published) containing data or other material included in the submitted manuscript, must be sent to the Editor when the manuscript is submitted. Clearly label such material so as to avoid any confusion with the submitted manuscript. Normally it is regarded as acceptable to include in a detailed journal article material that has been presented previously in summary form in reviews, symposia, or conferences, provided appropriate citation is included.

Brief Communications

Manuscripts describing focused studies that are concise and of high impact to a field will be published as Brief Communications. This format is intended for the presentation of scientifically sound and novel research in a clear and concise fashion. The body of the paper should not exceed nine (9) pages of double-spaced text with references. Tables and Figures must also be kept to a minimum (no more than four). Formatting should otherwise follow the requirements for Research Articles.

Minireviews

The journal publishes review articles under the section heading "Minireviews." Although there is no page limit, the reviews are generally short (~20 pages of double-spaced text with references). They should reflect the state-of-the-art of the area being reviewed and often include a brief history of the field. There is no need to include an exhaustive literature survey. Emphasis upon a particular hypothesis or point of view or upon the personal opinions or interpretation of the writer or upon the work of the writer's laboratory is appropriate, provided that this focus is clearly indicated in the paper. Most reviews are submitted in response to an invitation from the Editor-in-Chief, and are subjected to the usual review process prior to publication. Unsolicited reviews and reviews solicited by the Associate Editors need to be approved by the Editor-in-Chief before receiving peer review.

Comments

The Journal, at the Editor-in-Chief's discretion, will publish, under the section heading "Comments," letters or essays from readers discussing articles that have recently appeared in the Journal or other timely topics of interest to the Journal's readership. The author of a letter or essay which is published accepts full responsibility for the contents of the letter. Letters discussing a published article may for example include supporting information, clarifications, criticisms, corrections, alternate interpretations or perspectives. Such letters will be sent to the corresponding author of that article prior to publication. If the corresponding or other author wishes, her/his response will be published together with the original letter. At the discretion of the editor, essays or letters discussing controversial issues may be sent to persons representing alternative viewpoints who will be encouraged to provide responses. If the Editor decides to publish such responses, they will be sent to the original author for comments prior to publication. In some cases, the Editor- in-Chief may send a letter or essay for outside review prior to deciding whether to publish it. The Society reserves the right to edit these communications without materially changing their meaning.


Original Research Articles

Style of Manuscripts

1. Manuscripts should be as concise as possible, yet sufficiently detailed to permit critical appraisal, and should generally not exceed 40 typed pages (including tables, charts and references).

2. The Title should be a declarative statement of key findings and should be limited to 15 words. Use of abbreviations in the title should generally be avoided. Research articles should be divided into an Abstract (maximum 300 words), keywords, Introduction, Materials and Methods, Results, and Discussion sections.

3. Figures. All figures should be cited consecutively by Arabic numerals in the text with figure legends typed on a separate sheet. Legends should contain sufficient experimental detail to permit the figures to be interpreted without reference to the text. Units should be clearly indicated in the figures themselves. All figures and illustrations are to be submitted in such form as to permit photographic reproduction without retouching or redrawing. Line drawings should be no larger than 8.5 x 11.5 inches overall (21 x 27.5 cm). The lettering should be large enough to allow a reduction of two thirds.

4. Tables. These should be numbered with Arabic numerals and cited consecutively in the text. Each table should be titled and double-spaced on a separate sheet. Refer to current issues of Experimental Biology and Medicine for the acceptable style of tables. The title of each table should clearly indicate the nature of the contents, and sufficient experimental detail should be included in footnotes to the entries in the table to permit the reader to interpret the results without reference to the text. Units must be clearly indicated for each of the entries in the table.

5. Footnotes. Footnotes in the text should be identified by superscripts consisting of Arabic numerals; footnotes in the tables should be identified by superscript lowercase letters a, b, c, etc., and placed at the bottom of the table.

a. Acknowledgments should be typed on a separate page and placed at the end of the text pages.

6. References.

a. Citations should be used to provide appropriate attribution and credit to previous investigators. Extensive citation should be avoided, if possible, while adhering to the applicable conventions of the scientific community. Authors are responsible for obtaining permission to reproduce from the appropriate sources cited in the text.

b. References should be arranged numerically at the end of the manuscript and cited in the text with Arabic numerals in parentheses, set on the text line. The references should be numbered consecutively in order of their citation.

Abbreviations of journal titles should follow the style used in Index Medicus with a complete list of authors for each reference. Please follow the style of capitalization and punctuation illustrated by the following examples:

1. (journal article) Upadhyay D, Kamp DW. Asbestos-induced pulmonary toxicity: Role of DNA damage and apoptosis. Exp Biol Med 228:650-659, 2003.

2. (Book) Abramson DI. Circulation in the Extremities. New York: Academic Press, p000, 1967.

3. (book chapter) Langford MP, Weigent DA, Stanton GJ, Baron S. Virus plaque-reduction assay for interferon: Miroplaque and regular macroplaque reduction assay. In: Pestka S, Ed. Methods in Enzymology. New York: Academic Press, Vol Part A 78: p000, 1981.

4. (journal article in press) Hylden JL, Wilcox GL. Intrathecal morphine in mice: A new technique. Eur J Pharmacol (in press: volume, year).

c. "Personal communication," "unpublished," and "submitted" must be excluded from the reference list and cited in a footnote. If a manuscript being cited has been accepted for publication, include it in the reference list, giving journal, volume, year as available. In general, citation of numerous abstracts is discouraged, although acceptable if necessary to provide proper attribution or credit.

7. Trade name, popular name or abbreviation when first used must be preceded by the chemical, scientific or technical name; thereafter, any of these names or abbreviations may be used. Trade names should begin with a capital letter. Structural formulas of chemicals should be used only when absolutely necessary. Abbreviations used should generally be those listed below. Units of weights, measures, etc., when used in conjunction with numerals, should be abbreviated and unpunctuated, e.g., 6 R, 3 g, 5 ml, 8%. The metric system for weights and measurement, degrees Celsius for temperature, and the 24-hour clock (e.g., 0500h) to express time should be used.

Abbreviations Contributors are requested to use the following abbreviations: calorie cal
centimeter cm
counts per minute cpm
cubic centimeter cm3
Curie Ci
degree Celsius (centigrade) °C
diameter diam
gram g
inside diameter i.d.
intramuscular im
intraperitoneal ip
intravenous iv
kilocalorie kcal
kilogram kg
liter spell out
meter m
microliter µl
micrometer µm
milligram mg
milliliter ml
millimeter mm
milliosmole mOsm
molal (concentration) m
molar (concentration) M
mole spell out
molecular weight mol wt
nanogram ng
nanometer nm
normal (concentration) N
osmole Osm
outside diameter o.d.
parts per million ppm
percent %
picogram pg
revolutions per minute rpm
second sec
specific activity sp act
square centimeter cm2
square meter m2
subcutaneous sc
volt V
volume vol

Review Process

Two reviewers will generally evaluate each manuscript on the basis of scientific rigor of the experimental design, adequacy of the data, validity of the conclusions, importance and originality of the studies, adequacy of the literature citations, clarity of the presentation, and interest to the Journal's readership. Manuscripts may be returned to the authors without detailed review if, in the opinion of the Editor-in-Chief, they fall outside the scope of interests of the Journal's readership or if they are not written in clear, concise and grammatical English.

Manuscripts will be given a quality (priority) ranking by each reviewer. Those manuscripts with low priority rankings will not be accepted even though they may have been classed as generally acceptable. If reviewers differ significantly in their opinions, decision will be based on the priority rankings and/or the opinion of an additional reviewer (arbiter). Manuscripts returned after revision based upon reviewers' comments will be sent back to the original reviewers together with the authors' responses.

The reviewers' comments will be held in confidence except as follows: (a) the reviewers' comments may be sent, in whole or in part, to the corresponding author;(b)after revision, each reviewer's comments will be sent, in whole or in part, to the other reviewers of the manuscript: and (c) in the event that there is a significant difference in opinion between or among the reviewers, the manuscript may be sent to an additional reviewer (arbiter) together with the comments, in whole or in part, of the other reviewers. In all cases, anonymity of the reviewers will be maintained.


Copyright

Authors submitting a manuscript do so on the understanding that if it is accepted for publication, copyright in the article, including the right to reproduce the article in all forms and media, shall be assigned exclusively to the Society. The Society will not refuse any reasonable request by an author for permission to reproduce any of their contributions to the Journal. Send requests for permission to reproduce items published in Experimental Biology and Medicine to:

Society for Experimental Biology and Medicine
Attn: Permissions Editor
197 West Spring Valley Avenue
Maywood, NJ 07607-1727
USA

Articles and any other materials published in the Experimental Biology and Medicine represent the opinions of the author(s) and should not be construed to reflect the opinions of the Editor(s), or the Society.

Submitted manuscripts and accompanying materials become the property of the Society, and the Society is not responsible for loss or damage to such materials. The manuscript must be accompanied by a covering letter. The letter must state that the non-signing author(s) have read and approved the manuscript. Any person cited in the manuscript as a source of "personal communication" or "unpublished data" must provide signed approval of such citation.

Authors of manuscripts describing original nucleotide or amino acid sequences must submit the sequence to Gen Bank and obtain an accession number from Gen Bank before publication of the manuscript. The accession number should be included in the manuscript as a footnote or in the appropriate figure legend.

When, as a result of reviewers' comments, it is necessary to revise a manuscript, it is recommended that, unless additional studies are required, the authors should resubmit the revised manuscript promptly; a delay of longer than four months may result in the revised manuscript receiving a lower priority.

If you have any questions regarding submission, please contact the Society office:

Tel: 201-291-9080
Fax: 201-291-2988
e-mail: sebm@inch.com

All manuscripts should be submitted to:

http://ebm.allentrack.net

NOTIFY THE EDITORIAL OFFICE AT LEAST ONE MONTH BEFORE CHANGE OF ADDRESS.

Page and Other Charges

1. Changes in proof should be absolutely minimal. Authors will be charged for excessive changes.

2. Colored illustrations will only be published if the authors cover the costs.

3. The authors are required to pay a part of the cost of publication in the form of a page charge of $50 per page. Manuscripts for which a member of the SEBM is an author are exempt from page charges. (Please note the name(s) of the member author(s) when submitting the manuscript). Authors lacking funding from grant or other sources may apply at the time of submission for a waiver of page charges. Apply for a waiver of page charges in your cover letter at the time of submission. Applications must be endorsed by a senior institutional official verifying that no funds are available for paying page charges. A waiver of page charges will not be granted once a manuscript has been accepted. Reprint orders of 1,000 or more should be discussed with the publisher and authors are generally expected to discourage circulation of reprints for commercial purposes.

Use of Human and Animal Subjects and Recombinant DNA

Studies involving human subjects must conform to the ethical standards set by the Belmont Report, Ethical Principles and Guidelines for the Protection of Human Subjects of Research; must have been reviewed and approved by the appropriate institutional Review Board (IRB); and must be presented in such a manner as to assure preservation of the anonymity of the subjects. It must be stated in the Materials and Methods section of the article that the study had been approved by the responsible IRB and that informed consent was obtained from research subjects or it must be explained why IRB review and /or informed consent were not required.

It is the Journal's policy that all studies involving the use of animals be conducted in compliance with applicable laws and regulations as well as the principles expressed in the National Institutes of Health, USPHS, Guide for the Care and Use of Laboratory Animals, and that the studies be conducted on animals that were lawfully acquired. Use of animals must have been approved by the Institution's Animal Care and Use Committee (IACUC) and this must be stated in the Materials and Methods section of the article. If the study was conducted in a jurisdiction where such review is not required, this should be noted in the Materials and Methods section. Experiments involving recombinant DNA must have been reviewed and approved as required by applicable laws and regulations.

Financial Support and Conflict of Interest

All grant, contract and industrial support of the work included in the manuscript must be acknowledged in a footnote to the title of the manuscript. Commercial relationships of any of the authors that might be viewed as representing a conflict of interest must be disclosed in a footnote to the applicable author's name. Such disclosure should be made on a separate page as it will not be sent to reviewers or influence editorial decisions but will be included in the published paper.

Corrections

Notice of errors introduced inadvertently into a manuscript during the publication process will be published under the heading "Errata."

Corrections authors may wish to make regarding errors that they introduced into the manuscript or into the data analysis or interpretation will be published under the section heading "Comments," together with any responses by dissenting authors.


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